LTCC based bioreactors for cell cultivation

Stem cell cultivation in bioreactors.

Cell-based therapies have generated great interest in the scientific and medical communities, and stem cells in particular are very appealing for regenerative medicine, drug screening and other biomedical applications. These unspecialized cells have unlimited self-renewal capacity and the remarkable ability to produce mature cells with specialized functions, such as blood cells, nerve cells or ...

Bioreactors and Cultivation Systems for Cell and Tissue Culture

Fluid dynamics and mixing behavior in orbitally shaken bioreactors for mammalian cell cultivation

Rationale and significance. Recombinant therapeutic proteins are frequently produced in mammalian cells cultivated in suspension in large-scale stirred tank bioreactors. There are three major drawbacks to stirred-tank bioreactors. First, they are expensive to purchase and maintain, limiting their availability to some potential users. Second, they have not been adapted to volumetric scales less ...

Large scale cultivation of plant cell and tissue culture in bioreactors

Bioactive compounds extracted from plants are widely used. The natural habitats for a large number of plants are rapidly destroyed leading to extinction of many valuable and even endemic species. Studies on the production of plant metabolites by callus and cell suspension cultures have been carried out on an increasing scale since the end of the 1950's. The prospect of using such culturing tech...

Cell Culture Bioreactors

Cell Culture Bioreactors Basic Types of Bioreactors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1 Stirred Tank (Well Mixed) vs. Tubular Reactor (Plug Flow) . . . . . . . . . . . . . . . . . 3 Segregated Bioreactors (Dead Zone Present) Compartmentalized Bioreactors . . 4 Implication When Growth or Reaction Occurs in the Reactor . . . . . ....